Sustained release ophthalmic vehicle

Details Sustained release ophthalmic vehicle Sustained release ophthalmic vehicle

A - Human Necessities

61

K

167/159

A61K 9/16 (2006.01) A61K 9/00 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2027607

F1014 NON-SOLID OPHTHALMIC COMPOSITION AND PROCESS FOR PREPARING SAID COMPOSITION ABSTRACT The present invention relates to a non-solid ophthalmic composition, characterized in that it contains a suspension of microparticles in a non-solid medium compatible with ophthalmic application, the said solid microparticles having at least a pH of dissolution lying between approximately pH 4.5 and pH 8.5, the composition having a pH which does not permit dissolution of the microparticles before application but the formulation and the pH of the said composition being such that the neutralizing action of the lachrymal fluid can bring the pH back to the pH of dissolution.

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