A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/08 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 47/30 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01)
Patent
CA 2347104
Sustained-release particles prevented from sticking during compaction in the production of an oral sustained-release tablet, which comprise a drug- containing core substance coated with a film of a mixture of a hydrophobic organic compound and a water-insoluble polymer and have an average particle diameter of 300 µm or smaller; a process for producing the particles; and a process for producing a tablet from the sustained-release particles.
L'invention concerne des particules à libération prolongée ne collant pas au compactage, lors du processus de production d'un comprimé oral à libération prolongée. Ces particules contiennent une substance d'âme médicamenteuse enrobée d'une couche d'un mélange d'un composé organique hydrophobe et un polymère insoluble dans l'eau, et présentent un diamètre de la particule moyen d'au plus 300 µm. L'invention concerne également un procédé de production de ces particules, et un procédé de production d'un comprimé à partir des particules à libération prolongée.
Ikegami Kengo
Ishibashi Takashi
Mizobe Masakazu
Nagao Keigo
Yoshino Hiroyuki
Kirby Eades Gale Baker
Tanabe Seiyaku Co. Ltd.
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