Sustained release pharmaceutical composition

Details Sustained release pharmaceutical composition Sustained release pharmaceutical composition

A - Human Necessities

61

K

167/166, 167/209

A61K 31/55 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/50 (2006.01)

Patent

CA 1332567

- 9 - ABSTRACT SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION A sustained-release pharmaceutical composition which comprises microparticles comprising an active principle, said microparticles being coated with a coating mixture comprising ethyl cellulose and an acrylic resin which is a polymerisate of acrylic and methacrylic ester, having a molecular weight of at least 100,000 and comprising units of formula: Image wherein: R1 is hydrogen or methyl, R2 is methyl or ethyl, R3 is methyl; and R4 is -CH2-CH2N(CH3)3Cl the resin containing 5% of trimethylammonium methacrylate chloride units by weight.

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