Sustained release pharmaceutical composition

Details Sustained release pharmaceutical composition Sustained release pharmaceutical composition

A - Human Necessities

61

K

A61K 9/58 (2006.01) A61K 9/00 (2006.01) A61K 9/52 (2006.01) A61K 31/365 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61K 38/22 (2006.01) A61K 38/37 (2006.01) A61K 38/43 (2006.01) A61K 39/002 (2006.01) A61K 39/02 (2006.01) A61K 39/12 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 1/04 (2006.01) A61P 7/04 (2006.01) A61P 29/00 (2006.01) A61P 33/10 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2452030

A sustained release apparatus including a plurality of sustained release mini- implants or pellets; each mini-implant including a sustained release support material; and a pharmaceutically active composition carried in or on the sustained release support material; the pharmaceutically active composition including at least one pharmaceutically active component; and a carrier therefor; each implant being of insufficient size and/or payload individually to provide a predetermined desired threshold blood level of pharmaceutical active for treatment of a selected indication.

L'invention concerne un appareil de libération prolongée comprenant plusieurs mini-implants ou comprimés de libération prolongée. Chaque mini-implant comprend un matériau support de libération prolongée, et une composition active au niveau pharmaceutique placée dans ou sur le matériau support de libération prolongée. La composition active au niveau pharmaceutique comprend au moins un constituant actif au niveau pharmaceutique et un support pour celui-ci. Chaque implant possède une taille et/ou une charge utile individuelles insuffisantes pour obtenir une concentration sanguine seuil voulue prédéterminée d' un agent pharmaceutique actif dans le traitement d'une indication choisie.

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