A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/405 (2006.01) A61K 47/38 (2006.01) A61P 3/06 (2006.01)
Patent
CA 2346868
The present invention is directed to solid, sustained-release, oral dosage form pharmaceutical compositions which contain therapeutic amounts of a pharmaceutically active agent, hydroxypropyl methyl cellulose and anon-ionic, hydrophilic polymer selected from the group consisting of hydroxyethyl cellulose having a number average molecular weight ranging from 90,000 to 1,300,000, hydroxypropyl cellulose having a number average molecular weight of 370,000 to 1,500,000, and poly(ethylene oxide) having a number average molecular weight ranging from 100,000 to 500,000.
L'invention concerne des compositions pharmaceutiques à libération durable sous forme posologique orale solide qui contiennent des doses thérapeutiques d'un agent pharmaceutiquement actif, l'hydroxypropylméthylcellulose et un polymère hydrophile non ionique choisi dans le groupe composé d'hydroxyéthylecellulose d'un poids moléculaire moyen en nombre allant de 90 000 à 1 300 000, d'hydroxypropylcellulose d'un poids moléculaire moyen en nombre allant de 370 000 à 1 500 000, et un poly(éthylène oxyde) d'un poids moléculaire moyen en nombre allant de 100 000 à 500 000.
Patel Arun P.
Sandry Roy T.
Shah Rajen
Fetherstonhaugh & Co.
Novartis Ag
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