A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/26 (2006.01)
Patent
CA 2647421
Sustained release pharmaceutical composition comprising at least one poorly soluble active agent(s), at least one solubilizer, a release rate controlling polymer system consisting of an acid-soluble polymer and a pH-dependent polymer, and optionally other pharmaceutically acceptable excipients. The present invention also describes a process for preparation of such compositions and method of using such compositions. The sustained release compositions are useful in providing therapeutically effective levels of active agent(s) for extended periods of time.
La présente invention concerne une composition pharmaceutique à libération prolongée comprenant au moins un ou des agents actifs peu solubles, au moins un solubilisant, un système polymère régulant la vitesse comprenant un polymère soluble dans l'acide et un polymèr dépendant du pH, et facultativement d'autres excipients acceptables d'un point de vue pharmaceutique. L'invention concerne également un procédé de préparation de telles compositions et leur procédé d'utilisation. Les compositions à libération prolongée sont utilisables pour fournir des taux efficaces d'un point de vue thérapeutique du ou des agents actifs pendant des durées prolongées.
Devarajan Sampath Kumar
Jain Rajesh
Jindal Kour Chand
Panacea Biotec Ltd.
Sim & Mcburney
LandOfFree
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