Sustained release pharmaceutical preparations containing an...

A - Human Necessities – 61 – K

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A61K 31/165 (2006.01) A61K 9/24 (2006.01)

Patent

CA 2014418

ABSTRACT OF THE DISCLOSURE An orally administerable sustained-release pharmaceutical tablet having at least two layers, which are directly compressible, is disclosed. The first layer, an immediate-release layer, contains an orally active analgesic and is readily susceptible to disintegration in the stomach. The second layer, a sustained-release layer which is directly compressed onto the first layer, comprises an orally active decongestant admixed with a major amount of a sustained-release agent so as to display increased resistance to disintegration and erosion in the gastro-intestinal tract relative to the first layer. SF1K8029.DOC 4/4/89 30-2

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