A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/16 (2006.01) A61K 9/22 (2006.01)
Patent
CA 2572928
Disclosed herein are a sustained-release topiramate preparation and a method for producing the topiramate preparation. The sustained-release topiramate preparation is produced using double granules obtained by granulating topiramate or a pharmaceutically acceptable salt thereof using a solid dispersant by a solid dispersion method (first granulation), and further by granulating the granules using a release sustaining material by dry or wet granulation (second granulation).
L'invention concerne une préparation à libération lente contenant du topiramate, ainsi qu'un procédé de fabrication de cette préparation de topiramate. La préparation de topiramate à libération lente est fabriquée à partir de granules doubles obtenues par granulation de topiramate, ou d'un sel de celui-ci pharmaceutiquement acceptable, au moyen d'un dispersant solide par un procédé de dispersion solide (première granulation), puis par granulation des granules au moyen d'une substance à libération lente par granulation sèche ou humide (seconde granulation).
Kim Jung Ju
Park Jin Woo
Shin Kwang Hyun
Shin Young Hee
Amorepacific Corporation
Kirby Eades Gale Baker
LandOfFree
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