Sustained release therapeutic compositions

Details Sustained release therapeutic compositions Sustained release therapeutic compositions

A - Human Necessities

61

K

167/169

A61K 9/20 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1141295

ABSTRACT OF THE DISCLOSURE Shaped pharmaceutical tablets, lozenges, suppositories and other solid dosage unit forms which have a prolonged and regular release pattern of a therapeutically active medicament incorporated therein, wherein the shaped dosage unit comprises a carrier base material of hydroxypropylmethylcellulose or a mixture thereof with up to 30% ethylcellulose and/or up to 30% sodium carboxymethylcellulose and wherein the carrier base material is subjected to hydrolysis and oxidation so as to generate thereon a desired minimum concentration of carbonyl and carboxyl groups, and then admixed and shaped with a therapeutically active medicament.

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