Syndecan enhancer element and its use for targeting gene...

Details Syndecan enhancer element and its use for targeting gene... Syndecan enhancer element and its use for targeting gene...

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C12N 5/10 (2006.01) C12N 15/67 (2006.01)

Patent

CA 2272851

A syndecan enhancer element, novel proteins that activate the enhancer element, non-human transgenic animals comprising this enhancer element linked to a structural gene, and the use of this enhancer element to regulate the expression of syndecan and other genes are also provided. The enhancer element can also be used to target expression of a gene to wound sites.

L'invention concerne un élément stimulateur de syndecane, des nouvelles protéines qui activent ledit élément activateur, des animaux transgéniques non humains comprenant ledit élément stimulateur lié à un gène structural et l'utilisation de cet élément stimulateur pour la régulation de l'expression de syndecane et d'autres gènes. Ledit élément stimulateur peut également être utilisé pour diriger l'expression d'un gène sur des sites de blessures.

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