Synergism of hiv reverse transcriptase inhibitors

Details Synergism of hiv reverse transcriptase inhibitors Synergism of hiv reverse transcriptase inhibitors

A - Human Necessities

61

K

A61K 31/505 (2006.01) A61K 31/395 (2006.01) A61K 31/44 (2006.01) A61K 31/52 (2006.01) A61K 31/70 (2006.01) C07D 213/64 (2006.01) C07D 213/74 (2006.01) C07D 239/52 (2006.01) C07D 405/04 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 473/30 (2006.01) C07H 19/00 (2006.01)

Patent

CA 2054529

83/RDM47 18248IA TITLE OF THE INVENTION SYNERGISM OF HIV REVERSE TRANSCRIPTASE INHIBITORS ABSTRACT OF THE DISCLOSURE The combination of certain aminopyridones and anti-HIV nucleoside analogs has been found to synergistically inhibit HIV reverse transcriptase. This combination is useful in the prevention of treatment of infection by HIV and the treatment of AIDS, either as a combination of compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in further combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

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