Synergistic antimicrobial compositions

A - Human Necessities – 01 – N

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A01N 63/02 (2006.01) A01N 63/00 (2006.01) A23B 4/20 (2006.01) A23L 3/3526 (2006.01) A23L 3/358 (2006.01) A61K 38/44 (2006.01)

Patent

CA 2043463

ABSTRACT OF THE INVENTION The invention discloses an antimicrobial compo- sition composed of an antimicrobial polypeptide and a hypothiocyanate component. Synergistic activity is seen when the composition is applied at between about 30 and 40 degrees Centigrade at a pH between about 3 and about 5. The composition is useful against gram negative bacteria such as Salmonella and E. coli. A preferred composition is nisin, lactoperoxidase, thiocyanate and hydrogen peroxide. Such a composition is capable of reducing the viable cell count of Salmonella by greater than 6 logs in 10 to 20 minutes. MS #1624.1

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