Synergistic combinations of carotenoids and polyphenols

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/352 (2006.01) A61K 31/01 (2006.01) A61K 31/015 (2006.01) A61K 31/047 (2006.01) A61K 31/05 (2006.01) A61K 31/192 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2749202

The present invention provides a therapeutic composition comprising one or more polyphenols and two or more carotenoids selected from the group consisting of lutein, lycopene and beta- carotene. The invention also provides methods for in-hibiting or reducing the production of superoxide ions, NO, TNF-alpha and/or PGE2 in a mammalian subject comprising adminis-tering to said subject the aforementioned therapeutic composition.

La présente invention concerne une composition thérapeutique comprenant un ou plusieurs polyphénols et deux caroténoïdes ou davantage, choisis dans le groupe constitué de la lutéine, du lycopène et du bêta-carotène. L'invention concerne également des procédés permettant d'inhiber ou de réduire la production d'ions superoxyde, de NO, de TNF-alpha et/ou de PGE2 chez un sujet mammifère, procédés comprenant l'administration audit sujet de la composition thérapeutique susmentionnée.

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