A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/436 (2006.01) A61K 31/203 (2006.01) A61K 31/216 (2006.01) A61K 31/4436 (2006.01) A61P 17/00 (2006.01)
Patent
CA 2518245
Additive or synergistic combinations of a macrolide T-cell immunomodulator or immunosuppressant such as 33~epichloro-33-desoxyascomycin and a retinoid, such as etretinate, isotretinoin or tazarotene, optionally with a further pharmaceutically active agent, especially an antibacterial, are provided, which are useful in particular in the treatment of dermatological diseases such as eczema, atopic dermatitis, acne, psoriasis, skin aging, sun damage, post-peel erythema and stretch marks.
L'invention concerne des combinaisons additives ou synergistiques d'un immunomodulateur ou immunosuppresseur de lymphocyte T macrolide, tel que 33-épichloro-33-désoxyascomycine et d'un rétinoïde, tel que l'étrétinate, l'isotrétinoïne ou le tazarotène, éventuellement conjointement avec un autre agent actif sur le plan pharmaceutique, notamment un agent anti-bactérien, lesquelles sont utiles notamment dans le traitement de maladies dermatologiques, telles que l'eczéma, la dermatite atopique, l'acné, le psoriasis, le vieillissement de la peau, des lésions engendrées par le soleil, l'érythème provoqué par un peeling et des marques d'étirement.
Grassberger Maximilian
Hirsch Stefan
Mayer Friedrich Karl
Meingassner Josef Gottfried
Paul Carle
Fetherstonhaugh & Co.
Novartis Ag
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