A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/64 (2006.01) A61K 31/4166 (2006.01) A61K 31/437 (2006.01) A61K 31/444 (2006.01) A61K 31/4453 (2006.01) A61K 31/4545 (2006.01) A61K 31/455 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61K 31/501 (2006.01) A61K 45/06 (2006.01) A61P 3/10 (2006.01) A61P 27/12 (2006.01)
Patent
CA 2343850
The present invention provides methods of treating non-insulin dependent diabetes mellitus, insulin resistance, Syndrome X, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, polycystic ovary syndrome, cataracts, hyperglycemia, or impaired glucose tolerance, the methods comprising the step of administering to a patient having or at risk of having non- insulin dependent diabetes mellitus, insulin resistance; Syndrome X, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, polycystic ovary syndrome, cataracts, hyperglycemia, or impaired glucose tolerance a synergistic amount of:1 ) a sulfonylurea, a non-sulfonyllurea K+ ATP channel blocker, or a sulfonylurea and a non-sulfonylurea K+ ATP channel blocker; and 2) a cAMP phosphodiesterase type 3 inhibitor. The present invention also provides kits and pharmaceutical compositions that comprise: 1 ) a sulfonylurea, a non- sulfonylurea K+ ATP channel blocker, or a sulfonylurea and a non-sulfonylurea K+ ATP channel blocker; and 2) a cAMP phosphodiesterase type 3 inhibitor. The present invention also relates to kits and pharmaceutical compositions that comprise 1 ) a sulfonylurea, a non-sulfonylurea K+ ATP channel blocker, or a sulfonylurea and a non- sulfonylurea K+ ATP channel blocker; 2) a cAMP phosphodiesterase type 3 inhibitor; and 3) an additional compound useful for the treatment of non-insulin dependent diabetes mellitus, insulin resistance, Syndrome X, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, diabetic cardiomyopathy, polycystic; ovary syndrome, cataracts, hyperglycemia, or impaired glucose tolerance.
Fryburg David Albert
Parker Janice Catherine
Pfizer Products Inc.
Smart & Biggar
LandOfFree
Synergistic effect of a sulfonylurea and/or non-sulfonylurea... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Synergistic effect of a sulfonylurea and/or non-sulfonylurea..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synergistic effect of a sulfonylurea and/or non-sulfonylurea... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1911329