Syntheses of a variety of lamellarin compounds and analogues

C - Chemistry – Metallurgy – 07 – D

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C07D 491/14 (2006.01) A61K 31/435 (2006.01) C07D 207/34 (2006.01)

Patent

CA 2334322

The present invention relates to methods for preparing a variety of Lamellarin compounds and analogues via a synthetic intermediate, which methods involved the step of performing an intramolecular cyclization of a compound of Formula (I) to produce compounds of Formula (II), wherein the variables are given in the specification.

La présente invention concerne des procédés portant sur la préparation d'une variété de composés à base de lamellarine et de leurs analogues en utilisant un intermédiaire synthétique. Un tel procédé implique la réalisation d'une cyclisation intramoléculaire d'un composé représenté par la première formule générale (I) donnant des composés représentés par la seconde formule générale (II). En l'occurrence, les variables sont telles que décrites dans les spécifications.

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