Syntheses of d-chiro-3-inosose and (+)-d-chiro-inositol

C - Chemistry – Metallurgy – 07 – C

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C07C 35/16 (2006.01) C07C 29/145 (2006.01) C07C 49/497 (2006.01) C07D 317/46 (2006.01) C07D 317/62 (2006.01) C07D 493/04 (2006.01) C07D 493/14 (2006.01)

Patent

CA 2146353

There are described novel biocatalytic and chemical processes for the synthesis of various oxygenated compounds. Particularly, there are described processes for the synthesis of a useful synthon (12) made by reacting a protected diol (acetonide) with permanganate under appropriate conditions. Such synthon is useful of the synthesis of various pharmaceutically important compounds such as D-chiro-inositol and D-chiro-3-inosose. Also, there are disclosed novel compounds, including specifically the synthon (12) and compounds derived therefrom.

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