A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/454 (2006.01) C07D 401/04 (2006.01)
Patent
CA 2457319
The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, nitrogen-substitutued thalidomide analogs and di-substituted thalidomide analogs have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
La présente invention concerne un groupe de composés qui inhibent l'angiogenèse. Plus particulièrement, il a été démontré que des analogues de thalidomide substitués par azote et des analogues de thalidomide disubstitués inhibent l'angiogenèse. Ces composés peuvent vraiment être administrés par voie orale.
Conner Barry P.
D'amato Robert
Hunsucker Kimberly A.
Pribluda Victor
Rougas John
Entremed Inc.
Smart & Biggar
The Children's Medical Center Corporation
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