C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 407/06 (2006.01) A61K 31/351 (2006.01) A61K 31/365 (2006.01) A61P 35/00 (2006.01) C07D 309/10 (2006.01)
Patent
CA 2615112
The invention relates to the synthesis and complete stereochemical assignments of cytotoxic compounds such as compound 28-a and its stereoisomers. The invention further provides processes for making the compounds, their synthetic intermediates, and for methods of using the compounds and their pharmaceutical compositions for the treatment of neoplastic diseases.
La présente invention concerne la synthèse et les attributions stéréochimiques complètes de composés cytotoxiques, tels que le composé 28-a et ses stéréoisomères. La présente invention concerne également des procédés permettant de fabriquer ces composés; leurs produits intermédiaires de synthèse ainsi que des méthodes permettant d'utiliser ces composés et les compositions pharmaceutiques destinées au traitement de maladies néoplasiques.
de Brabander Jef
Jiang Xin
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Board Of Regents University Of Texas System
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