Synthesis and immunogenicity of rotavirus genes using...

Details Synthesis and immunogenicity of rotavirus genes using... Synthesis and immunogenicity of rotavirus genes using...

C - Chemistry, Metallurgy

12

N

167/130, 167/140

C12N 15/33 (2006.01) A61K 39/12 (2006.01) A61K 39/42 (2006.01) C07K 14/14 (2006.01) C12N 15/86 (2006.01) C12N 15/866 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1339732

A method to express rotavirus genes in a baculovirus system. Different clones are used to express rotavirus genes for all of the viral proteins. These proteins are isolated in their native conformation. Some of these proteins show antigenic properties and are used to vaccinate human, agricultural animals and pet animals against diarrheal disease. The antigenic proteins are also used to detect the presence of the viral infectious agent either by themselves or in conjunction with antibodies produced against the antigenic proteins.

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