Synthesis and uses of 2-oxo-4-methylthiobutyric acid, its...

C - Chemistry – Metallurgy – 07 – C

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C07C 323/52 (2006.01) A23K 1/16 (2006.01) C07C 319/18 (2006.01) C07C 319/20 (2006.01) C07C 323/60 (2006.01)

Patent

CA 2592588

The invention concerns a method for preparing 2-oxo-4-methylthiobutyric acid (I), its salts and its derivatives of formula (I) wherein: R represents a group selected among COOH, COOR', NH2, NHR', NR'R" where R' and R" are selected, independently of each other, from the group of linear or branched alkyl radicals having 1 to 12 carbon atoms, and cycloalkyl radicals having 3 to 12 carbon atoms. Said method consists in the catalytic and selective oxidation of but-3-ene-1,2-diol (II) into 2-oxo-but-3-enoic acid (III) and in selectively condensing the methylmercaptan on the 2-oxo-but-3-enoic acid (III). The 2- oxo-4-methylthiobutyric acid (I), its salts and its derivatives are used as food complement, in particular for animal feeding.

L'invention concerne un procédé pour préparer l'acide 2-oxo-4- méthylthiobutyrique (I), ses sels et ses dérivés formule (I) dans laquelle R représente un groupement choisi parmi COOH, COOR', NH2, NHR', NR'R" où R' et R" sont choisis, indépendamment l'un de l'autre, dans le groupe des radicaux alkyles linéaires ou ramifiés ayant de 1 à 12 atomes de carbone, et des radicaux cycloalkyles ayant de 3 à 12 atomes de carbone, procédé selon lequel on effectue l'oxydation catalytique et sélective du but-3-ène-1 ,2-diol (II) en acide-2-oxo-but-3-ènoïque (III) et on condense sélectivement le méthylmercaptan sur l'acide-2-oxo-but-3-ènoïque (III). L'acide 2-oxo-4- méthylthiobutyrique (I), ses sels et ses dérivés sont utilisés comme complément alimentaire, notamment en nutrition animale.

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