Synthesis, methods of using, and compositions of...

Details Synthesis, methods of using, and compositions of... Synthesis, methods of using, and compositions of...

C - Chemistry, Metallurgy

07

C

C07C 215/28 (2006.01) A61K 31/135 (2006.01) A61P 25/24 (2006.01) C07C 47/46 (2006.01) C07C 215/42 (2006.01) C07C 255/46 (2006.01) C07C 311/03 (2006.01) C07C 311/04 (2006.01) C07C 313/06 (2006.01) C07F 5/02 (2006.01)

Patent

CA 2436899

The invention realtes, in part, to making of making and using, and compositions comprising, racemic and stereomerically pure cyclobutylalkylamines, including hydroxylated sibutramine and hydroxylated metabilites of sibutramine. Methods of treating and preventing a variety of diseases and disorders are disclosed, as are pharmeaceutical compositions and unit dosage forms that comprise compounds of the invention.

Cette invention concerne pour partie la fabrication et l'utilisation de compositions renfermant des cyclobutylalkylamines racémiques et stéréomèriquement pures dont une sibutramine hydroxylée et des métabilites hydroxylées de sibutramine. L'invention porte également sur des méthodes de traitement et de prévention applicables à divers troubles et pathologies, ainsi que sur des compositions pharmaceutiques et des formes de dosage unitaires renfermant les composés de l'invention.

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