Synthesis of...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 305/18 (2006.01) A61K 31/59 (2006.01) C07C 69/07 (2006.01) C07C 69/08 (2006.01) C07C 69/732 (2006.01) C07C 255/37 (2006.01) C07C 401/00 (2006.01)

Patent

CA 2676512

The invention provides a method of producing 20-methyl vitamin D3 compounds of formula (I). The method includes hydroxylation, carbonyl reduction, fluoride substitution, epoxide deoxygenation, and Wittig-type couplings.

L'invention porte sur une méthode de production de composés 20-méthyle de la vitamine D3 de formule (I). Ladite méthode comporte les étapes suivantes: hydroxylation, réduction du carbonyle, substitution du fluorure, désoxygénation des époxides, et couplages de type Wittig.

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