C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/6561 (2006.01) C07C 273/18 (2006.01) C07C 275/24 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2416906
A novel process for the preparation of (R)-3-(4-Bromobenzyl)-1-(3,5- dichlorophenyl)-5-iodo-3-methyl-1-H-imidazo[1,2-a]imidazol-2-one (1). This compound is useful as an intermediate in the preparation of certain small molecules that are useful in the treatment or prevention of inflammatory and immune cell-mediated diseases. The present invention also relates to certain intermediates used in this novel process.
L'invention concerne un nouveau procédé de préparation de (R)-3-(4-Bromobenzyl)-1-(3,5-dichlorophényl)-5-iodo-3-méthyl-1-H-imidazo[1,2-a]imidazol-2-one (1). Ce composé est utilisé en tant qu'intermédiaire dans la préparation de certaines molécules de faible dimension utilisées dans le traitement ou la prévention des maladies inflammatoires et immunes à médiation cellulaire. La présente invention concerne également certains intermédiaires utilisés dans ce nouveau procédé.
Frutos Rogelio P.
Johnson Michael Dale
Boehringer Ingelheim Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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