Synthesis of 2-alkoxyestradiols

Details Synthesis of 2-alkoxyestradiols Synthesis of 2-alkoxyestradiols

C - Chemistry, Metallurgy

07

J

C07J 1/00 (2006.01)

Patent

CA 2283436

Disclosed is a method of preparing a compound represented by structural formula (a). The method comprises reacting bromine (Br2) and an aliphatic organic acid with a compound represented by structural formula (b). R1 and R2 are each independently a hydroxyl protecting group.

L'invention concerne un procédé de préparation d'un composé représenté par la formule de structure suivante (a). Le procédé comporte l'étape consistant à faire réagir du brome (Br¿2?) et un acide organique aliphatique avec un composé représenté par la formule de structure suivante (b). R¿1? et R¿2? représentent chacun indépendamment un groupe hydroxyle de protection.

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