Synthesis of 2-chloromethyl-6-methylbenzoic acid esters

Details Synthesis of 2-chloromethyl-6-methylbenzoic acid esters Synthesis of 2-chloromethyl-6-methylbenzoic acid esters

C - Chemistry, Metallurgy

07

C

C07C 69/94 (2006.01) C07D 263/32 (2006.01)

Patent

CA 2519715

The invention relates to a method for producing compounds of formula (I) wherein R represents H, optionally halogen-substituted alkyl, cycloalkyl or aryl, alkyl-aryl or heteroaryl, and at least one CH2 group can be replaced by O in alkyl and cycloalkyl. Said compounds of formula (I) are valuable intermediates in the synthesis of PPAR agonists.

L'invention concerne un procédé de fabrication de composés de formule (I), dans laquelle R désigne un H, un alkyle, cycloalkyle, aryle, alkyl-aryle ou hétéroaryle éventuellement substitué par un halogène, un ou plusieurs groupes CH¿2? pouvant être remplacés par O- dans l'alkyle ou le cycloalkyle. Les composés de formule (I) sont des produits intermédiaires précieux pour la synthèse d'agonistes PPAR.

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