Synthesis of 2'-deoxy-l-nucleosides

C - Chemistry – Metallurgy – 07 – H

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07H 1/08 (2006.01) A61K 31/7052 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07H 1/06 (2006.01) C07H 19/06 (2006.01) C07H 19/16 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2391279

This invention provides processes for the preparation of compounds having structure (A) wherein X and Y are same or different, and H, OH, OR, SH, SR, NH2, NHR', or NR'R"; Z is H, F, Cl, Br, I, CN or NH2. R is hydrogen, halogen, lower alkyl of C1-C6 or aralkyl, NO2, NH2, NHR', NR'R", OH, OR, SH, SR, CN, CONH2, CSNH2, CO2H, CO2R', CH2CO2H, CH2CO2R', CH=CHR, CH2CH=CHR, or C=CR. R' and R" are same or different, and lower alkyl of C1-C6. R13 is hydrogen, alkyl, acyl, phosphate (monophosphate, diphosphate, triphosphate, or stabilized phosphate) or silyl.

L'invention concerne des techniques de préparation de composés dont la structure est représentée par la formule (I). Dans cette formule, X et Y sont identiques ou différents, et représentent H, OH, OR, SH, SR, NH¿2?, NHR', ou NR'R"; Z représente H, F, Cl, Br, I, CN ou NH¿2?; R représente hydrogène, halogène, alkyle inférieur C¿1?-C¿6? ou aralkyle, NO¿2?, NH¿2?, NHR', NR'R", OH, OR, SH, SR, CN CONH¿2?, CSNH¿2?, CO¿2?H, CO¿2?R', CH¿2?CO¿2?H, CH¿2?CO¿2?R', CH=CHR, CH¿2?CH=CHR, ou C=CR; R' et R" sont identiques ou différents, et représentent alkyle inférieur C¿1?-C¿6?; R?13¿ représente hydrogène, alkyle, acyle, phosphate (monophosphate, diphosphate, triphosphate, ou phosphate stabilisé) ou silyle.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Synthesis of 2'-deoxy-l-nucleosides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Synthesis of 2'-deoxy-l-nucleosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Synthesis of 2'-deoxy-l-nucleosides will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1856969

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.