Synthesis of 2-isopropylamino pyrimidine

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

CPC

260/263

IPC codes

C07D 239/42 (2006.01) C07D 239/38 (2006.01)

Type

Patent

Patent number

CA 1132563

Description

A B S T R A C T The present invention provides a process for the synthesis of 2-isopropylamino-pyrimidine by aminolysis of 2-methylsulphonyl-pyrimidine using isopropylamine. The aminolysis is effected, according to the present invention, by refluxing isopropylamine and 2-methylsulphonyl- pyrimidine in the absence of a solvent. Using this technique, the 2-isopropylamino-pyrimidine has been obtained in a substantially quantitative yield.

Application Number

355324

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