C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/10 (2006.01)
Patent
CA 2515138
Provided is a novel method of making 2-butyl-3-[[2'(1-trityl-1H-tetrazol-5- yl)biphen-4-yl]methyl]1,3-diazaspiro[4,4]non-1-ene-4-one, which can be converted to irbesartan. Also provided are methods of making irbesartan.
La présente invention concerne un nouveau procédé de production de 2-butyl-3-[[2'(1-trityl-1H-tétrazol-5-yl)biphén-4-yl]méthyl]-1,3-diazaspiro[4,4]non-1-én-4-one pouvant être converti en irbesartan. Cette invention concerne également des procédés de production d'irbesartan.
Dolitzky Ben-Zion
Kaftanov Julia
Nisnevich Gennady
Pertsikov Boris
Rukhman Igor
Heenan Blaikie Llp
Teva Pharmaceutical Industries Ltd.
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