Synthesis of...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 495/04 (2006.01)

Patent

CA 2558654

The invention belongs to the field of organic chemistry and relates to a new process for the purification of olanzapine comprising preparation of acid addition salts of olanzapine and transformation thereof into a pharmaceutically acceptable pure and discoloured final product. The present invention also relates to new processes for the preparation of pure olanzapine.

Cette invention se rapporte au domaine de la chimie organique et concerne une nouvelle méthode de purification d'olanzapine. La méthode consiste à préparer des sels d'addition acide d'olanzapine et à transformer ces sels en un produit fini pur et décoloré pharmaceutiquement acceptable. L'invention concerne en outre de nouvelles méthodes de préparation d'olanzapine pure.

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