Synthesis of 6,7-dihydro-1h-indeno[5,4-b]furan-8(2h)-one as...

Details Synthesis of 6,7-dihydro-1h-indeno[5,4-b]furan-8(2h)-one as... Synthesis of 6,7-dihydro-1h-indeno[5,4-b]furan-8(2h)-one as...

C - Chemistry, Metallurgy

07

D

C07D 307/77 (2006.01) C07D 307/79 (2006.01)

Patent

CA 2730224

The present invention describes the preparation of 6, 7 -dihydro-1H-indeno[5, 4 -b] furan-8 (2H) -one of formula V, a key intermediate in preparation of ramelteon. The present invention also describes further preceding intermediate compounds useful for the synthesis of 6, 7-dihydro-1H-indeno[5, 4-b] furan-8 (2H) -one.

La présente invention porte sur la préparation de la 6,7-dihydro-1H-indéno[5,4-b]furan-8(2H)-one de formule V, un intermédiaire-clé dans la préparation du rameltéon. La présente invention porte également sur des composés intermédiaires précédents utiles pour la synthèse de la 6,7-dihydro-1H-indéno[5,4-b]furan-8(2H)-one.

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