Synthesis of a 3,4-dihydroxy-1- cyclopentanylpurinone from a...

C - Chemistry – Metallurgy – 07 – D

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C07D 473/18 (2006.01) C07H 1/06 (2006.01)

Patent

CA 2079960

Abstract Synthesis of the triol of formula (I) or its amine-protected derivative from a cyclopentene of the formula (II) or its amine-protected derivative: Image Image (II) (I) via steps including oxidation to the aldehyde, migration of the double bond, reduction of the aldehyde moiety back to the alcohol grouping and 1,2-cis- dihydroxylation of the double bond. -42- GLX-37

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