Synthesis of acyclic nucleoside derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 473/18 (2006.01) C07C 67/08 (2006.01) C07C 69/12 (2006.01) C07C 69/22 (2006.01) C07C 303/30 (2006.01) C07C 309/73 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2723085

Methods and novel intermediates for the preparation of acyclic nucleoside derivatives of formula (I) where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a -C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.

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