Synthesis of amines and intermediates for the synthesis thereof

C - Chemistry – Metallurgy – 07 – D

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C07D 209/38 (2006.01) C07D 209/16 (2006.01) C07D 209/18 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2508290

The invention relates in a first embodiment to a method for the manufacture of esters of the formula (I), or especially of amides of the formula (II), wherein the symbols have the meanings given in the specification, as well as other intermediates and compounds useful in the synthesis of tryptamines and other substances mentioned in the title. The synthesis methods and intermediates are useful in the synthesis of pharmaceuticals.

Dans un premier mode de réalisation, cette invention concerne un procédé pour fabriquer des esters représentés par la formule (I), notamment des amides représentés par la formule (II), où les symboles sont tels que définis dans les pièces descriptives de la demande, ainsi que d'autres intermédiaires et composés utiles dans la synthèse de tryptamines et d'autres substances mentionnées dans le titre. Ces procédés de synthèse et ces intermédiaires sont utiles dans la synthèse de produits pharmaceutiques.

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