Synthesis of boronic ester and acid compounds

Details Synthesis of boronic ester and acid compounds Synthesis of boronic ester and acid compounds

C - Chemistry, Metallurgy

07

F

C07F 5/02 (2006.01) C07F 5/04 (2006.01)

Patent

CA 2560886

The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.

La présente invention concerne la synthèse d'ester borique et de composés acides. Plus particulièrement, cette invention concerne des processus synthétiques améliorés en vue d'une production à grande échelle d'ester borique et de composés acides, comprenant bortézomibe inhibiteur de protéasome d'acide borique peptidique.

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