Synthesis of carbamate ketolide antibiotics

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 17/08 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2321336

The invention relates to a method of preparing a macrolide antibiotic of the formula Image wherein R1, R2, R3, R4, R5 are defined above. These antibiotics are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention also includes novel compounds made by the preparation of the macrolide antibiotic.

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