Synthesis of chiral 2-azetidinemethanol compounds

Details Synthesis of chiral 2-azetidinemethanol compounds Synthesis of chiral 2-azetidinemethanol compounds

C - Chemistry, Metallurgy

07

D

C07D 205/04 (2006.01) C07C 69/76 (2006.01) C07C 69/78 (2006.01) C07C 309/66 (2006.01)

Patent

CA 2395169

A process for preparing chiral isomers of N-protected 2-azetidinemethanol compounds of formula (5), particularly N-(phenylmethyl)-2-azetidinemethanol and N-BOC-2-azetidinemethanol, and especially the (R)-isomers thereof, as well as O-substituted derivatives thereof.

L'invention concerne un procédé de préparation d'isomères chiraux de composés de 2-azétidineméthanol à protection N de la formule (5), en particulier le N-(phénylméthyl)-2-azétidineméthanol et le N-BOC-2-azétidineméthanol et notamment leurs isomères R, ainsi que leurs dérivés à substitution O.

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