Synthesis of chiral amines

Details Synthesis of chiral amines Synthesis of chiral amines

C - Chemistry, Metallurgy

07

B

C07B 43/04 (2006.01) C07B 53/00 (2006.01)

Patent

CA 2728552

The instant invention involves the enantioselective hydrogenation of isomeric N-H imines (N-unsubstituted) using a transition metal based catalyst modified with a chiral phosphine derivative to produce enantiomerically enriched chiral amines.

Cette invention concerne lhydrogénation énantiosélective dimines N-H isomères (non substituées en N) en utilisant un catalyseur à base de métal de transition modifié avec un dérivé de phosphine chirale pour produire des amines chirales enrichies énantiomériquement.

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