Synthesis of chirally purified substituted benzothiazole...

Details Synthesis of chirally purified substituted benzothiazole... Synthesis of chirally purified substituted benzothiazole...

C - Chemistry, Metallurgy

07

D

C07D 277/82 (2006.01) C07B 57/00 (2006.01)

Patent

CA 2681110

Methods for preparing chirally purified substituted 4,5,6,7-tetrahydro-benzotiazole diamines such as, for example, (6R)2-amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole and purifying a dominant enantiomer of substituted 4,5,6,7-tetrahydro-benzotiazole diamines from entantiomerically enriched mixtures of substituted 4,5,6,7-tetrahydro-benzotiazole diamines are provided herein.

L'invention concerne des procédés de préparation de 4,5,6,7-tétrahydro-benzothiazole diamines substituées et purifiées du point de vue chiral telles que, par exemple, le (6R)2-amino-4,5,6,7-tétrahydro-6-(propylamino)benzothiazole et de purification d'un énantiomère dominant de 4,5,6,7-tétrahydro-benzothiazole diamines substituées à partir de mélanges énantiomériquement enrichis de 4,5,6,7-tétrahydro-benzothiazole diamines substituées.

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