Synthesis of glycerol di- and triphosphate derivatives

C - Chemistry – Metallurgy – 07 – H

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C07H 19/04 (2006.01) C07F 9/547 (2006.01) C07H 19/20 (2006.01)

Patent

CA 2083961

2083961 9118914 PCTABS00008 A process for the preparation of glycerophospholipid derivatives comprising coupling the phosphate group of a glycerol monophosphate derivative in which one of the phosphate hydroxyls is replaced by a leaving group, with the terminal phosphate group of a mono- or diphosphate compound or a salt thereof, in the presence of a basic catalyst, under anhydrous conditions.

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