Synthesis of long-chain polyunsaturated fatty acids by...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A01H 5/00 (2006.01) C11B 1/00 (2006.01)

Patent

CA 2563875

The present invention relates to methods of synthesizing long-chain polyunsaturated fatty acids, especially eicosapentaenoic acid, docosapentaenoic acid and docosahexaenoic acid, in recombinant cells such as yeast or plant cells. Also provided are recombinant cells or plants which produce long-chain polyunsaturated fatty acids. Furthermore, the present invention relates to a group of new enzymes which possess desatorase or elongase activity that can be used in methods of synthesizing long-chain polyunsaturated fatty acids.

L'invention concerne des procédés permettant de synthétiser des acides gras polyinsaturés à chaîne longue, notamment les acides eicosapentanoïque, docosapentanoïque et docosahexanoïque, dans des cellules de recombinaison telles que des cellules de levure ou végétales. L'invention concerne également des cellules de recombinaison ou des plantes qui produisent des acides gras polyinsaturés à longue chaîne. En outre, elle concerne un groupe de nouveaux enzymes qui possèdent une activité désaturase ou élongase que l'on peut utiliser dans des procédés de synthèse d'acides gras polyinsaturés à chaîne longue.

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