Synthesis of methoxy nucleosides and enzymatic nucleic acid...

C - Chemistry – Metallurgy – 07 – H

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C07H 21/02 (2006.01) C07H 19/04 (2006.01) C07H 19/06 (2006.01) C07H 19/09 (2006.01) C07H 19/16 (2006.01) C07H 21/00 (2006.01) C12N 9/22 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2253382

This invention relates to chemical synthesis of 2'-O-methyl, 3'-O-methyl and 5'-O-methyl nucleosides, incorporation of novel chemical modifications in enzymatic nucleic acid molecules and improved methods for the synthesis of enzymatic nucleic acid molecules.

Cette invention concerne la synthèse chimique de 2'-O-méthyl, de 3'-O-méthyl et de 5'-O-méthyl-nucléosides, l'incorporation de nouvelles modifications chimiques dans des molécules d'acide nucléique enzymatique et des procédés améliorés pour la synthèse de molécules d'acide nucléique enzymatique.

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