Synthesis of phenolic esters of hydroxymethyl phenols

C - Chemistry – Metallurgy – 07 – C

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C07C 213/06 (2006.01) C07C 219/28 (2006.01)

Patent

CA 2648333

The present invention provides a process for the production of a compound of formula (I) or a salt thereof, wherein R is hydrogen, a straight, branched or cyclic C1-C6 alkyl group or an aryl group which may optionally be substituted. This process comprises: (a) reacting a compound of formula (II), with a compound of formula (III), wherein R is as defined above and X is a leaving group, in the presence of N, N-diisopropylethylamine.

La présente invention concerne un procédé de production d'un composé répondant à la formule (I) ou d'un sel de celui-ci, dans laquelle R représente un atome d'hydrogène, un groupe alkyle en C1 à C6 ramifié ou cyclique ou un groupe aryle qui peut éventuellement être substitué. Ce procédé comprend : (a) la réaction d'un composé répondant à la formule (II) avec un composé répondant à la formule (III), dans laquelle R est tel que défini ci-dessus et X représente un groupe partant, en présence de N,N-diisopropyléthylamine.

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