Synthesis of protected 3'-amino nucleoside monomers

Details Synthesis of protected 3'-amino nucleoside monomers Synthesis of protected 3'-amino nucleoside monomers

C - Chemistry, Metallurgy

07

H

C07H 19/06 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2571601

Orthogonally protected 3'-amino nucleoside monomers and efficient methods for their synthesis are described. The methods employ selective protection of the 3'-amino group in the presence of the unprotected nucleoside base.

L'invention concerne des monomères nucléosidiques à groupe 3'-amino orthogonalement protégé ainsi que des procédés efficaces pour leur synthèse. Ces procédés permettent une protection sélective du groupe 3'-amino en présence de la base nucléosidique non protégée.

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