C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 473/00 (2006.01) C07D 473/34 (2006.01)
Patent
CA 2488562
The present invention provides a process for producing highly substituted purine compounds from pyrimidine compounds. Furthermore, processes of the present invention allow preparation of a library of purine compounds. Specifically the invention claims a process for the preparation of a substituted purine compound of the formula (I), wherein R1, R2, R3, R4, and R5 are as described herein.
La présente invention a trait à un procédé destiné à produire des composés puriques à forte substitution à partir de composés pyrimidiques. Les procédés selon la présente invention permettent également la préparation d'une banque de composés puriques. L'invention concerne précisément un procédé de préparation d'un composé purique substitué représenté par la formule (I), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, et R?5¿ sont tels que définis dans le descriptif de l'invention.
Hammarstroem Lars G. J.
Krauss Nancy Elisabeth
Labadie Sharada Shenvi
Smith David Bernard
Talamas Francisco Xavier
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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