Synthesis of salmon calcitonin

Details Synthesis of salmon calcitonin Synthesis of salmon calcitonin

C - Chemistry, Metallurgy

07

K

530/7.36

C07K 14/585 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1055930

SYNTHESIS OF SALMON CALCITONIN ABSTRACT OF THE DISCLOSURE Resin peptides useful in the preparation of salmon calcitonin are disclosed along with processes for preparing the same. The invention also embraces peptides from which the resin moiety has been cleaved and which are use- ful in the synthesis of salmon calcitonin together with processes for preparing the cleaved peptides. In general, the processes involve the solid phase synthesis procedures. The invention deals with new compounds containing an amino acid chain similar to that of salmon calcitonin and new methods for closing the ring strucutre in such compounds to produce calcitonin.

233063

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