C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 405/12 (2006.01)
Patent
CA 2666685
A process for producing one selected stereoisomer of a substituted alcohol comprises reacting a stereoisomeric epoxide with an amine, a carboxylic acid, an amide, a sulfonyl, or a cyanide. The process avoids the production of a racemic mixture of stereoisomers of the prior art. Such a stereoisomeric substituted alcohol can be used for anti-inflammatory therapy.
L'invention concerne un procédé de production d'un stéréoisomère sélectionné d'un alcool substitué. Ledit procédé consiste à faire réagir un époxyde stéréoisomérique avec une amine, un acide carboxylique, un amide, un sulfonyle, ou un cyanure. Le procédé permet d'éviter la production d'un mélange racémique de stéréoisomères de l'état antérieur de la technique. Un tel alcool substitué stéréoisomérique peut être utilisé en tant que traitement anti-inflammatoire.
Bausch & Lomb Incorporated
Osler Hoskin & Harcourt Llp
LandOfFree
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