Synthesis of soluble beta-sheet forming peptides

Details Synthesis of soluble beta-sheet forming peptides Synthesis of soluble beta-sheet forming peptides

C - Chemistry, Metallurgy

07

K

C07K 14/00 (2006.01) A61K 38/16 (2006.01) A61P 31/04 (2006.01) A61P 35/00 (2006.01) C07K 1/00 (2006.01) C07K 2/00 (2006.01) C07K 14/47 (2006.01) C07K 14/52 (2006.01) C07K 14/54 (2006.01) C07K 14/655 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2255865

This invention relates to the chemical design and production of peptides, peptide structure and three dimensional conformation was assessed using NMR, circular dichroisin and pulsed field gradient NMR. In addition, this invention relates to peptides produced by these methods and to methods for using the peptides.

L'invention concerne la conception et la production de peptides par des moyens chimiques; l'estimation de la structure des peptides et de leur conformation en trois dimensions est effectuée à l'aide de la R.M.N. à gradient du dichroïsme circulaire et de la R.M.N. en champ pulsé. L'invention se rapporte également à des peptides obtenus par ces procédés et à des méthodes d'utilisation desdits peptides.

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