Synthesis of thiazoles

C - Chemistry – Metallurgy – 07 – D

Patent

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260/302, 260/278

C07D 277/14 (2006.01) C07D 277/28 (2006.01) C07D 417/06 (2006.01)

Patent

CA 1217486

Abstract Certain 4-halomethylthiazoles having a 2- substituted-aminomethyl group are prepared by reacting an aminothioamide with a dihalopropanone in the presence of a haloalkane and a bicarbonate, and dehydrating the resulting intermediate.

454003

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