Synthetic antigen for the detection of antibodies...

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/70 (2006.01) C07K 7/00 (2006.01) C07K 14/00 (2006.01) C07K 14/16 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2298438

Novel polypeptides, and recombinant polynucleotide sequences encoding the same, are provided. The polypeptides have substantially the same sequence as immunologically significant fragments of AIDS-related viruses. The polypeptides can be used as reagents in the determination of exposure of a human host to the virus. Of particular interest is the use of polypeptides in screening blood products.

La présente invention concerne de nouveaux polypeptides et des séquences de polynucléotides recombinants les codant. Les polypeptides possèdent sensiblement la même séquence que les fragments immunologiquement importants des virus liés au sida. Les polypeptides peuvent être utilisés comme réactifs dans la détermination de l'exposition d'un hôte humain au virus. Par ailleurs, l'utilisation des polypeptides dans les tests sanguins de dépistage est particulièrement intéressante.

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